Cardbox Server or Cardbox Client? ;-)
If I Google I see it is a normal Server 2016 with some hardware limitations and you can use it for max 25 accounts. So I expect no trouble with it.
But if you want to know for sure, an evaluation version you can download on https://www.microsoft.com/en-us/evalcenter/evaluate-windows-server-2016-essentials.
It is easy to day to try it!